Publications

• In situ observation of rapid ligand exchange in colloidal nanocrystal suspensions using transfer NOE nuclear magnetic resonance spectroscopy.
  Fritzinger, I. Moreels, P. Lommens, R. Koole, Z. Hens, J.C. Martins,
  J. Am. Chem. Soc., 131, in press (2009)

• “Structure and X-ray conformation of pseudodesmins A and B, two new cyclic lipodepsipeptides from Pseudomonas bacteria”
  D. Sinnaeve, C. Michaux, J. Van Hemel, J. Vandenkerckhove, E. Peys, F. A. M. Borremans, B. Sas, J. Wouters and J. C. Martins
  Tetrahedron, 65, 4173-4181, (2009)

• “Solubilization of flurbiprofen within non-ionic Tween 20 surfactant micelles: a 19F and 1H NMR study”
  P. Saveyn, E. Cocquyt, W. Zhu, D. Sinnaeve, K. Haustraete, J. C. Martins and P. Van der Meeren
  Physical Chemistry Chemical Physics, 11, 5462-5468 (2009)

• 'Click' Functionalization of Cryogels Conveniently Verified and Quantified Using High-Resolution MAS NMR Spectroscopy
  Van Camp, W.; Dispinar, T.; Dervaux, B.; Du Prez, F. E.; Martins, J. C.; Fritzinger, B.
  Macromolecular Rapid Communications , 30, 1328-1333 (2009)

• Towards the conformational mimicry of the measles virus HNE loop: design, synthesis and biological evaluation of a cyclic bile acid–peptide conjugate
  C.A. Bodé, T. Bechet, E. Prodhomme, K. Gheysen, P. Gregoir, J.C. Martins, C.P. Muller and A. Madder
  Org.Biomol.Chem., 7, 3391-3399 (2009)

• Application of a Combined Weak Cation-Exchange/Crown Ether Column: First Demonstrations of a Versatile Tool for Proteome Subselection
  R. Tuytten, B. Ruttens, K. Gheysen, K. Sandra, K. De Cremer, D. Vlieghe, N. Van Landuyt, G. Thomas, J.C. Martins, P. Sandra, K. Kas and K. Verleysen
  Anal.Chem., 81, 2456-2469 (2009)

• Indenylidene Complexes Of Ruthenium Bearing NHC Ligands – Structure Elucidation And Performance As Catalysts For Olefin Metathesis
  Stijn Monsaert, Els De Canck, Renata Drozdzak, Pascal Van Der Voort, Francis Verpoort, José C. Martins and Pieter M.S. Hendrickx
  European Journal Of Organic Chemistry ,655–665(2009)

• The use of time-averaged 3JHH restrained molecular dynamics (tar-MD) simulations for the conformational analysis of five-membered ring systems: Methodology and applications
  Pieter M. S. Hendrickx, Francisco Corzana, Stefaan Depraetere, Dirk A. Tourwé, Koen Augustyns, José C. Martins
  J. Comput. Chem. 2009 (In Press) DOI:10.1002/jcc.21345

• Predicting the effect of a point mutation on a protein fold: The villin and advillin headpieces and their Pro62Ala mutants.
  Piana, S., Laio, A., Marinelli, F., Van Troys, M., Bourry, D., Ampe, C. and Martins, J. C.
  J. Mol. Biol. 375, 460-470 (2008)

• NMR study of the sorption behavior of benzyl alcohol derivatives into sonicated and extruded dioctadecyldimethylammonium chloride (DODAC) dispersions: the relevance of membrane fluidity.
  Saveyn, P., Cocquyt, E., Sinnaeve, D., Topgaard, D., Martins, J.C. and Van der Meeren, P.
  Langmuir, 24, 3082-3089, (2008)

• Advanced polymer architectures with stimuli-responsive properties starting from inimers.
  Bernaerts, K. V., Fustin, C.-A., Bomal-D’Haese, C., Gohy, J. F., Martins, J. C. and Du Prez, F. E.
  Macromolecules 41, 2593-2606 (2008)

• Quantification of hydrolytic charge loss of DMAEA-Q based polyelectrolytes by proton NMR spectroscopy and implications for colloid titration
  Saveyn, H., Hendrickx, , P. M. S., Dentel, S. K., Martins, J. C. and Van der Meeren, P.
  Water Research 42, 2718-2728(2008)

• NMR-based characterization of metabolic alterations in hypertension using a novel adaptive, intelligent binning algorithm
  De Meyer, T., Sinnaeve, D., Van Gasse, B., Tsiporkova, E., Rietzschel, E. R., De Buyzere, M. L., Gillebert, T. C., Bekaert, S., Martins, J. C. and Van Criekinge, W.
  Anal. Chem. 80, 3783-3790 (2008)

• Sandwich -ELISE NMR : reducing the sample volume of NMR samples
  Wieruszeski, J. M., Fritzinger, B., Hanoulle X., Martins, J. C. and Lippens, G.
  J. Magn. Reson. 193, 37-40 (2008)

• Sn12O8(OH)4(OEt)28(HOEt)4 : an additional member in the family of dodecameric oxo-clusters.
  Ribot, F., Martinez-Ferrero, E., Boubekeur, K., Hendrickx, P. M. S., Martins, J. C., Van Lokeren, L., Willem, R. and Biesemans, M.
  Inorg. Chem. 47, 5841-5850 (2008)

• Spectroscopic Evidence of Thermally Induced Metamorphosis in ethylene-bridged periodic mesoporous organosilicas
  Vercaemst, C., Jones, J. T. A., Khimyak, Y. Z., Martins, J. C., Verpoort, F. and Van Der Voort, P.
  Phys. Chem. Chem. Phys. 10, 5349-5352 (2008)

• A user-friendly Matlab program and GUI for the pseudorotation analysis of saturated five-membered ring systems based on scalar coupling constants
  Hendrickx, P. M. S. and Martins, J. C.
  Chemistry Central Journal , 2:20 (2008)

• Rapid identication of hexapyranose units via a simple TOCSY matching approach
  Gheysen, K., Mihai, C., Conrath, K., and , Martins, J. C.
  Chem. Eur. J. 14, 8869-8878 (2008)

• Surface Chemistry of colloidal PbSe nanocrystals
  Moreels, I., Fritzinger, B, Martins, J. C., and Hens, Z.
  J. Am. Chem. Soc. 130,15081-15086 (2008)

• Characterization of titanium dioxide nanoparticles dispersed in organic ligand solutions by using a diffusion-ordered spectroscopy-based strategy.
  Van Lokeren, L., Maheut, G., Ribot, F., Escax, V., Verbruggen, I., Sanchez, C., Martins, J. C., Biesemans, M. and Willem, R.
  Chem. Eur. J. 13, 6957-6966 (2007)

• A polystyrene-supported tin trichloride catalyst with a C11-spacer. Catalysis monitoring using high-resolution magic angle spinning NMR.
  Pinoie, V., Poelmans, K., Miltner, H. E., Verbruggen, I., Biesemans, M., Van Assche, G., Van Mele, B., Martins, J. C. and Willem, R.
  Organometallics 26, 6718-6725 (2007)

• Synthesis and complete NMR characterization of methacrylateendcapped poly(ortho-esters).
  Paesen, B., Baekelandt, T., Heller, J., Martins, J. C. and Schacht, E. H.
  E-Polymers 13 (2007)

• Composition and size-dependent extinction coefficient of colloidal PbSe quantum dots.
  Moreels, L., Lambert, K., De Muynck, D., Vanhaecke, F., Poelman, D., Martins, J. C., Allan, G. and Hens, Z.
  Chem. Mat. 19, 6101-6106 (2007)

• Solution NMR techniques for investigating colloidal nanocrystal ligands:
  A case study on trioctylphosphine oxide at InP quantum dots
  Moreels, I., Martins, J.C. and Hens, Z.
  Sensors and Actuators B, in press (2007)
  

• Synthesis and Biological Evaluation of Bicyclic Nucleosides as Inhibitors of M. tuberculosis Thymidylate Kinase.
  Van Daele, I., Munier-Lehmann, H., Hendrickx , P., Froeyen, M., Rozenski, J., Qing, L., Martins, J. C., Van Calenbergh, S.
  ChemMedChem in press (2006)
  
  
• Solid-Supported Synthesis of Highly Functionalized Tripodal Peptides with Flexible but Preorganized Geometry: Towards Potential Serine Protease Mimics
  Gea, A., Roqué i Rossell, N., Farcy, N., Martins, J. C., Madder, A. and De Clercq , P.J., Eur. J.
  Org. Chem., 18, 4135-4146 (2006)
  

• Ligand Adsorption/Desorption at Sterically Stabilized InP Colloidal Nanocrystals: observation and thermodynamic analyis.
  Moreels, I.; Martins, J. C. and Hens, Z.
  ChemPhysChem,7, 1028-1031 (2006)
  
  
• Identification of the PXW Sequence as a Structural Gatekeeper of the HeadPiece C-terminal  Subdomain Fold.
  Vermeulen, W.; Van Troys, M.; Bourry, D.; Dewitte, D.; Rossenu, S.; Goethals, M., Borremans, F. A. M., Vandekerckhove, J., Martins, J. C. and Ampe C.
  J. Mol. Biol., 359, 1277–1292 (2006)

• Polystyrene-Supported Organotin Dichloride as a Recyclable Catalyst in Lactone Ring-Opening Polymerization: Assessment and Catalysis Monitoring by High-Resolution Magic-Angle-Spinning NMR Spectroscopy.
  Deshayes, G.; Poelmans, K.; Verbruggen, I.; Camacho-Camacho, C.; Degée, P.; Pinoie, V.; Martins, J. C.; Piotto, M.; Biesemans, M.; Willem, R. and Dubois, P.
  Chem. Eur. J. 11, 4550-4559 (2005)

• In situ evaluation of interfacial affinity of CeO2 based hybrid nanoparticles by pulsed field gradient NMR.
  Ribot, F.; Escax, V.; Roiland, C.; Sanchez, C.; Martins, J. C.; Biesemans, M.; Verbruggen, I. and Willem, R.
  Chem. Comm. 1019-1021 (2005)

• How Thioredoxin can reduce a buried disulfide bond.
  Messens, J.; Van Molle, I.; Vanhaesebrouck, P.; Limbourg, M.; Van Belle, K.; Wahni , K.; Martins , J. C.; Loris , R. and Wyns , L.
  J. Mol. Biol. 339, 527-537 (2004)

• The structure of a triple mutant of pI258 arsenate reductase from Staphylococcus aureus and its 5-thio-2-nitrobenzoic acid adduct.
  Messens, J.; Van Molle, I.; Vanhaesebrouck, P.; Van Belle, K.; Wahnia, K.; Martins, J. C.; Wyns, L. and Loris, R.
  Acta Cryst. D 60, 1180-1184 (2004)

• Solution structures of the C-terminal headpiece subdomains of human villin and advillin, evaluation of headpiece F-actin binding requirements.
  Vermeulen, W.; Vanhaesebrouck, P.; Van Troys, M.; Verschueren, M.; Fant, F.; Goethals, M.; Ampe, C.; Martins, J. C. and Borremans, F. A. M.
  Protein Science 13, 1276-1287 (2004)

• Interface Synthesis, Characterization and Catalytic Properties of Dialkyldichlorotin and Tetra-alkyl Distannoxane Functionalities Grafted to Insoluble Polystyrene Beads by a Hexamethylene Spacer.
  Biesemans, M.; Mercier, F. A. G.; Van Poeck, M.; Martins, J. C.; Dumartin, G. and Willem, R.
  Eur. J. Inorg. Chem. 2908-2913 (2004)

• Assessing weak intramolecular donor-acceptor interactions using 1H- 117 Sn J-HMQC spectroscopy.
  Biesemans, M.; Martins, J. C.; Jurkschat, K.; Pieper, N.; Seemeyer, S. and Willem, R.
  Magn. Res. Chem. 42, 776-780 (2004)

• Probing Ionic Association on Metal Oxide Clusters by Pulsed field Gradient NMR : the Example of tin-12 Oxo-Clusters.
  Ribot, F.; Escax, V.; Martins, J. C.; Biesemans, M.; Ghys, L.; Verbruggen I. and Willem, R.
  Chem. Eur. J. 10, 1747-1751 (2004)

2002

• All intermediates of the arsenate reductase mechanism, including an intramolecular dynamic disulfide cascade.
  Messens, J.; Martins, J. C.; Van Belle, K.; Brosens, E.; Desmyter, A.; De Gieter, M.; Wieruszeski, J.-M.; Willem, R.; Wyns, L and Zegers, I.
  Proc. Natl. Acad. Sci. USA 99, 8506-8511 (2002)
  
  
• Fine-tuned characterization at the solid/solution interface of organotin compounds grafted on cross-linked polystyrene using high resolution MAS NMR spectroscopy.
  Martins, J. C.; Mercier, F. A. G.; Vandervelden, A.; Biesemans, M.; Wieruszeski, J. M.; Humpfer, E.; Willem, R. and Lippens, G.
  Chem. Eur. J. 8, 3431-3441 (2002)
  
  
• Active Site Loop Dynamics and Protein Stability Kinetics of S. aureus Arsenate Reductase.
  Messens, J.; Martins, J. C.; Brosens, E.; Van Belle, K.; Jacobs, D. M.; Willem, R.
  and Wyns, L.
  J. Biol. Inorg. Chem . 7, 146-156 (2002)

• Complexation of Triorganotin Derivatives of 4-Carboxybenzo-18-Crown-6 and -15-Crown-5 with Alkali Thiocyanates.
  Tsagatakis, J.; Chaniotakis, N.; Altmann, R.; Jurkschat, K.; Martins, J. C.; Willem, R.; Qiu, Y. and Bakker, E.
  Helv. Chim. Acta 84, 1952-1961 (2001)

• Phosphate-Binding Characteristics and Selectivity Studies of Bifunctional Organotin Carriers.
  Kemmer, M.; Biesemans, M.; Gielen, M.; Martins, J. C.; Gramlich, V. and Willem, R.
  Chem. Eur. J. 7, 4686-4695 (2001)

• 1H, 13C and 15N Backbone Resonance Assignment of the Arsenate Reductase from Staphylococcus aureus in its Reduced State.
  Jacobs, D. M.; Messens, J.; Wechselberger, R.; Brosens, E.; Willem, R.; Wyns, L. and Martins, J. C.
  J. Biomol. NMR 20, 95-96 (2001)

• Solution Structure of the Main a -Amylase Inhibitor from Amaranth seeds.
  Martins, J. C.; Enassar, M.; Willem, R.; Wieruszeski, J.-M.; Lippens, G. and Wodak, S. J.
  Eur. J. Biochem. 269, 2379-2389 (2001)

• Unprecedented Sigmatropic Rearrangements leading to 2,3-Dihydro-1H-2-Benzazepine-3-Carboxylic acid.
  Martins, J. C.; Van Rompaey, K.; Wittmann, G.; Tömböly, C.; Toth, G.; De Kimpe, N. and Tourwé, D.
  J. Org. Chem. 66, 2884-2886 (2001)

• Di-n-Butyl Methyl- and Phenylphosphonates.
  Ribot, F.; Sanchez, C.; Biesemans, M.; Mercier, F. A. G.; Martins, J. C.; Gielen, M. and Willem, R.
  Organometallics 20, 2593-2603 (2001)

• Convenient Synthesis of 3,4-Methano-1,2,3,4- Tetrahydro-isoquinoline-3-Carboxylic Acid and its Derivatives as Double Constrained Nonproteinogenic amino acid derivatives. Csombos, J.; Aelterman, W.; Tkachev, A.; Martins, J. C.; Péter, A.; Toth, G.; Fülöng, F.; Tourwé, D. and De Kimpe N.
  J. Org. Chem. 65, 5469-5475 (2000)

• Reaction of BuSnO(OH) with p-toluenesulfonic acid: Synthesis, X-ray crystal Analysis and Multinuclear NMR Characterization of {(BuSn)12O14(OH)6}(PTS)2(PTS: p-toluenesulfonate).
  Eychenne-Baron, C.; Ribot, F.; Steunou, N.; Sanchez, C.; Fayon, F.; Biesemans, M.; Martins, J. C. and Willem, R.
  Organometallics 19, 1940-1949 (2000)

• Tin NMR Based Methodologies and their Use in Structural Tin Chemistry.
  Martins, J. C.; Biesemans, M. and Willem, R.
  Prog. NMR Spectrosc. 36, 271-322 (2000)

• 13C-119Sn Correlation NMR in Solution and 119Sn-13C CP/MAS NMR Spectra of Dibutyltin(IV) and Bis(tributylstannyl(IV)) L-(+) Ascorbates and O-5,6-Isopropylidene-L(+)-Ascorbates.
  Lycka, A.; Micak, D.; Holecek, J.; Biesemans, M.; Martins, J. C. and Willem, R.
  Organometallics 19, 703-706 (2000)

• Multinuclear 1D and 2D NMR Investigations on the Interaction between the Pyrimidic nucleotides 5'-CMP, 5'-dCMP and 5'-UMP and Diethyltin Dichloride in Aqueous Medium. Ghys, L.; Biesemans, M.; Gielen, M.; Garoufis, A.; Hadjiliadis, N.; Willem, R. and Martins, J. C.
  Eur. J. Inorg. Chem. 513-522 (2000)

• A Comparative Investigation of the Consistent Valence and Extensible Systematic Force Fields. A Case Study on the Conformation of Erythromycin A in Benzene.
  Martins, J. C.; Willem, R. and Biesemans, M.
  J. Chem. Soc., Perkin Trans. 2, 1513-1520 (1999)

• Tributyl- and Triphenyltin Benzoates, Phenylacetates and Cinnamates as Anion Carriers: an Electrochemical Assessment Coupled to Structural NMR Studies and AM1 Calculations.
  Tsagatakis, J. K.; Chaniotakis, N. A.; Jurkschat, K.; Damoun, S.; Geerlings, P.; Bouhdid, A.; Gielen, M.; Verbruggen, I.; Biesemans, M.; Martins, J. C. and Willem, R.
  Helv. Chim. Acta 82, 531-542 (1999)

• Modeling in Organotin Chemistry Using NMR Restraints: A Case Study on the 9R,12S[tBu 2 Sn] 2 O Derivative of Erythromycin A.
  Martins, J. C.; Willem, R.; Mercier, F. A. G.; Gielen, M.; Biesemans, M.
  J. Am. Chem. Soc. 121, 3284-3291 (1999)

• A Gene Encoding a Hevein-Like Protein from Elderberry (Sambucus nigra) Fruits is Homologous to PR-4 and Class V Chitinase Genes.
  Van Damme, E. J. M.; Charels, D.; Roy, S.; Tierens, K.; Barre, A.; Martins, J. C.; Rougé, P.; Van Leuven, F.; Does, M. and Peumans, W.
  Plant Physiol. 119, 1547-1556 (1999)

• Reconsidering the Energetics of Ribonuclease Catalysed RNA hydrolysis.
  Loverix, S.; Laus, G.; Martins, J. C.; Wyns, L. and Steyaert, J.
  Eur. J. Biochem. 257, 286-290 (1998)

• Reactions of [t-Bu2SnO]3 with [t-Bu2X2Si]2 (X= F,Cl). Synthesis and Structure of Novel Stannasiloxanes and of [(t-Bu2FSn)2O]2 , the first Fluorine-Containing Tetraorganodistannoxane.
  Beckmann, J.; Biesemans, M.; Hassler, K.; Jurkschat, K.; Martins, J. C.; Schürmann, M. and Willem, R.
  Inorg. Chem. 37, 4891-4897 (1998)

• Solution and Solid State Multinuclear NMR investigation of the Structure of {(BuSn)12O14 (OH)6}(O2PPh2)2.
  Ribot, F.; Sanchez, C.; Willem, R.; Martins, J. C. and Biesemans, M.
  Inorg. Chem. 37, 911-917 (1998)

• Synthesis, Molecular Structure, and Stereochemical Nonrigidity of Bis(3-(dimethylamino)propyl)difluorostannane Dihydrate, {[Me2N(CH2)3]2SnF2.2H2O} and Enhanced Reactivity of Its Fluoride Adduct {[Me2N(CH2)3]2SnFs}-Bu4N+ toward Dichloromethane.
  Pieper, N.; Klaus-Mrestani, C.; Schürmann, M.; Jurkschat, K.; Biesemans, M.; Verbruggen, I.; Martins, J. C. and Willem, R.
  Organometallics 16, 1043-1052 (1997)

• Optimal Detection of Weak nJ(1H-119Sn) Couplings by Gradient Enhanced 1D and 2D Heteronuclear Multiple-Quantum Correlation Spectroscopy. Application to a Novel Tin Derivative of Erythromycin A.
  Martins, J. C.; Kayser, F.; Gielen, M.; Willem, R. and Biesemans, M.
  J. Magn. Reson. 124, 218-222 (1997)

• Solution Conformation of Raphanus sativus Antifungal Protein 1 (Rs-AFP1) by 1H Nuclear Magnetic Resonance. Resonance Assignment, Secondary Structure and Global Fold.
  Fant, F.; Vranken, W. F.; Boulez, K.; Martins, J. C. and Borremans, F. A. M.
  Bull. Soc. Chim. Belg. 106, 51-57 (1997)

• Conformational Features of a Synthetic Cyclic Peptide Corresponding to the Complete V3 Loop of the RF-HIV-1 Strain in Water and Water/Trifluoroethanol Solutions.
  Vranken, W. F.; Budesinsky, M.; Martins, J. C.; Fant, F.; Boulez, K.; Gras-Masse, H. and Borremans, F. A. M.
  Eur. J. Biochem. 236, 100-108 (1996)

• Synthesis and Characterization of Triphenyl- and Tri-n-butyltin Pentafluoro benzoates, -Phenylacetates and -Cinnamates. X-ray Structure Determination of Tri-n-butyltin Pentafluorocinnamate.
  Willem, R.; Bouhdid, A.; Biesemans, M.; Martins, J. C.; De Vos, D.; Tiekink, E. R. T. and Gielen, M.
  J. Organomet. Chem. 514, 203-212 (1996)

• 1H NMR Study on the Inclusion of Bicyclo[3.3.1]nonanes in cyclodextrins.
  Butkus, E.; Martins, J. C. and Berg U.
  J. Incl. Phenom. Mol. 25, 125-128 (1996)

• X-ray Diffraction and 2D 1H-119Sn Gradient Assisted HMQC NMR Studies on the Structure of Condensation Complexes of Salicylaldoxime and Dimethyltin(IV) oxide.
  Willem, R.; Bouhdid, A.; Kayser, F.; Delmotte, A.; Gielen, M.; Martins, J. C.; Biesemans, M.; Mahieu, B. and Tiekink, E. R. T.
  Organometallics 15, 1920-1929 (1996)

• 1H NMR Spectroscopic Study of the Interaction between Cyclodextrins and Bicyclo[3.3.1]nonanes.
  Butkus, E.; Martins, J. C. and Berg U.
  J. Incl. Phenom. Mol. 26, 209-218 (1996)

• 1H NMR Study of the Interaction of N,N',N”-triacetyl-chitotriose with Ac-AMP2, a Sugar Binding Antimicrobial Protein Isolated from Amaranthus caudatus.
  Verheyden, P.; Pletinckx, J.; Maes, D.; Pepermans, H. A. M.; Wyns, L.; Willem, R. and Martins, J. C.
  FEBS Lett. 370, 245-249 (1995)

• A Comparative Structural Study on the Steroids [1,2,5]Oxadiazolo[3',4':3,4]-5-alpha-pregn-16-en-20-one oxime (HS998), [1,2,5]Oxadiazolo[3',4':3,4]-5-alpha-pregn-16-en-20-one (HS974) and [1,2,5]Oxadiazolo[3',4':3,4]-5-beta-pregn-16-en-20-one oxime (HS973) by NMR, Molecular Modeling and X-ray Investigations.
  Kayser, F.; Maes, D.; Wyns, L.; Lisgarten, J.; Palmer, R.; Lisgarten, D.; Willem, R.; Martins, J. C.; Verheyden, P. and Biesemans, M.
  Steroids 60, 713-719 (1995)

• Solution Conformation of Leiurotoxin I (Scyllatoxin) by 1H NMR. Resonance Assignment and Secondary Structure.
  Martins, J. C.; Zhang, W. and Borremans F. A. M.
  FEBS Lett. 260, 249-253 (1990)

• Isolation and Characterisation of Mutumol, 22-acetoxy-3 b ,23-dihydroxy-24-methylene-lanost-8-ene, from the East African Fungus Pisolithus Arhizus (Pers.) Rausch.
  Van Puyvelde, L.; De Kimpe, N.; Vanderick, F.; Costa, J.; Niyotwagira, V.; Borremans, F.; Martins, J.; Declercq, J.-P. and Schamp, N.
  Bull. Soc. Chim. Belg. 97, 901-909 (1988)